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Results from clinical trials of milk thistle for liver diseases, such as alcohol-related liver disease, hepatitis B and C, non-alcoholic fatty liver disease, and liver problems caused by cancer chemotherapy, low oxygen levels, or toxins have been conflicting or too limited to allow conclusions to be reached

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Common adverse effects (percent incidence) Serious risks include pancreatitis, gallbladder issues, and thyroid C-cell tumors (boxed warning for both)